Answer: A

Estrogen plays a role in both the male and female reproductive systems. In women, it can affect your reproductive and breast health as well as your bone and heart health.* Estrogen levels generally decline during perimenopause, but they do so in an irregular fashion.

*Cleveland Clinic. “Estrogen.” Page last reviewed February 8, 2022.
https://my.clevelandclinic.org/health/body/22353-estrogen